England have won their past 17 meetings with France in all competitions, but were pushed to within a point in a 43-42 victory in last year's Six Nations finale.
France, who have grown into the tournament as a new-look backline have found their feet, will be roared on by a crowd that is expected to set a new record for a Women's Six Nations match in France at the 42,000-capacity Stade Atlantique.
England's defence has been uncharacteristically lax in their last couple of matches, with both Italy and Wales taking try-scoring bonus points in defeat.
Head coach John Mitchell says some of those lapses have been the cost of installing an attacking mindset as part of the team's evolution.
"We'll just keep scoring more," he said.
"It's our new identity, it's the way that we're evolving our game.
"We realise we can't build everything in one tournament. So our intentions and our emphasis has certainly been in one area.
"It doesn't mean that we are not trying to fix a couple of areas in the ruck and maul and rotations might have played a part in that.
"For me, experience and defence are one of the easiest things to fix. Ultimately we will be stronger down the track for these learnings."
England: Kildunne; Breach, Jones (c), Rowland, Moloney-MacDonald; Harrison, L Packer; Carson, Cokayne, Bern, Ives Campion, Burns, Burton, Kabeya, Feaunati
Replacements: Powell, Crake, Muir, Short, M Packer, Robinson, Aitchison, Sing.