Fury weighed in at a career-high 20st 1lb as he looked to avenge the only defeat on his sparkling professional record and proceeded to dominate the opening exchanges of the fight.
As the rounds wore on, the boxing genius of Usyk started to get to grips with Fury as he landed blows of his own and pushed the pace of the bout.
Former WBO cruiserweight champion Johnny Nelson said on Sky Sports he had the fight "a little bit closer" than the judges.
"Usyk initiated almost everything in the fight and Tyson had to react," he said.
"Yes, it was close, I don't think the scorecards were like that. But I understand that Usyk did a great job. Frank [Warren] was saying he thought Tyson won.
"That's being a promoter. There's no way in a million years he thought Tyson won.
"The best man won on the night and got the job done."
Fury and Usyk's promoters had very different ideas on how the fight should have been scored with the Queensberry chief backing the Briton.
"How come Tyson only got four rounds in this fight? It's impossible," Warren said.
"He's very disappointed as I am as well. Everyone along the front [of the ring] thought it was all the same way."
Whereas Team Usyk's Alex Krassyuk thought Fury was right to have been given just four rounds.
"I had Fury three or four rounds," he said.
"The judges gave him four. That's the fairest score it could be."